The Orange and the Irish had been scheduled to play at Notre Dame Stadium in South Bend, Indiana.
The Yankee Stadium game is part of Notre Dame’s Shamrock Series.
“Yankee Stadium is one of the great venues in all of sports,” Syracuse head football coach Dino Babers said in a Syracuse news release. “To play a fantastic opponent like Notre Dame in that building, closer to home, I think is exciting for our fans. As coaches and players, it’s a once-in-a-lifetime experience and something we’re very much looking forward to.”
The Orange are 7-1 all-time at Yankee Stadium, with the last game being a 38-14 win over West Virginia in the 2012 New Era Pinstripe Bowl.
Notre Dame holds a 5-3 advantage in the all-time series against Syracuse. The Irish won the two most recent contests in 2014 and 2016 at MetLife Stadium in East Rutherford, N.J. Syracuse last beat the Irish in 2008 at Notre Dame Stadium, 24-23.
The Orange begin the 2018 football season on Sept. 1 at Western Michigan. Syracuse is coming off three straight 4-8 seasons, including the two seasons under Babers.
Contact Rombel at arombel@cnybj.com
File photo of Oct. 13, 2017 football game between Clemson and Syracuse by Adam Rombel/ BJNN